Scientific Publications

Non-invasive, Brain-controlled Functional Electrical Stimulation for Locomotion Rehabilitation in Individuals with Paraplegia

A. Selfslagh, S. Shokur*, D. S.F. Campos, A. R. C. Donati, S. Almeida, M. Bouri, M. A. L. Nicolelis (2019). Non-invasive, Brain-controlled functional electrical stimulation for locomotion rehabilitation in paraplegic patients. Scientific Reports. 9:6782. https://doi.org/10.1038/s41598-019-43041-9 (2019).

Training with brain-machine interfaces, visuo-tactile feedback and assisted locomotion improves sensorimotor, visceral, and psychological signs in chronic paraplegic patients

Solaiman Shokur, Ana R.C. Donati, Debora S.F. Campos, Claudia Gitti, Guillaume Bao, Dora Fischer, Sabrina Almeida, Vania A.S. Braga, Patricia Augusto, Chris Petty, Eduardo J.L. Alho, Mikhail Lebedev, Allen W. Song, Miguel A.L. Nicolelis. PLoS ONE 13(11):e0206464. https://doi.org/10.1371/journal.pone.0206464 (2018). 

Assimilation of virtual legs and perception of floor texture by complete paraplegic patients receiving artificial tactile feedback

Solaiman Shokur, Simone Gallo, Renan C. Moioli, Ana Rita C. Donati, Edgard Morya, Hannes Bleuler, Miguel A.L. Nicolelis. Assimilation of virtual legs and perception of floor texture by complete paraplegic patients receiving artificial tactile feedback. Scientific Reports. 6, 32293; doi:10.1038/srep32293 (2016).

Long-Term Training with a Brain-Machine Interface-Based Gait Protocol Induces Partial Neurological Recovery in Paraplegic Patients

Ana R. C. Donati, Solaiman Shokur, Edgard Morya, Debora S. F. Campos, Renan C. Moioli, Claudia M. Gitti, Patricia B. Augusto, Sandra Tripodi, Cristhiane G. Pires, Gislaine A. Pereira, Fabricio L. Brasil, Simone Gallo, Anthony A. Lin, Angelo K. Takigami, Maria A. Aratanha, Sanjay Joshi, Hannes Bleuler, Gordon Cheng, Alan Rudolph, Miguel A. L. Nicolelis. Long-Term Training with a Brain-Machine Interface-Based Gait Protocol Induces Partial Neurological Recovery in Paraplegic Patients. Scientific Reports. 6, 30383; doi: 10.1038/srep30383 (2016).

Spinal Cord Stimulation Alleviates Motor Deficits in a Primate Model of Parkinson Disease

Maxwell B. Santana, Pär Halje, Hougelle Simplício, Ulrike Richter, Marco Aurelio M. Freire, Per Petersson, Romulo Fuentes, Miguel A.L. Nicolelis. Spinal Cord Stimulation Alleviates Motor Deficits in a Primate Model of Parkinson Disease. Neuron, Volume 84, Issue 4, p716–722, 19 November 2014.

Reciprocal regulation of epileptiform neuronal oscillations and electrical synapses in the rat hippocampus

Erika R. Kinjo , Guilherme S. V. Higa, Edgard Morya, Angela C. Valle, Alexandre H. Kihara, Luiz R. G. Britto. Reciprocal regulation of epileptiform neuronal oscillations and electrical synapses in the rat hippocampus. PLoS One. 2014 Oct 9;9(10):e109149.

Joint Cross-Correlation Analysis Reveals Complex, Time-Dependent Functional Relationship Between Cortical Neurons And Arm Electromyograms

Katie Z. Zhuang, Mikhail A. Lebedev, Miguel A. L. Nicolelis. JOINT CROSS-CORRELATION ANALYSIS REVEALS COMPLEX, TIME-DEPENDENT FUNCTIONAL RELATIONSHIP BETWEEN CORTICAL NEURONS AND ARM ELECTROMYOGRAMS. J Neurophysiol. 2014 Sep 10:jn.00031.2013.

Basal forebrain dynamics during a tactile discrimination task

Eric Thomson, Jason Lou, Kathryn Sylvester, Annie McDonough, Stefani Tica, Miguel A. Nicolelis. Basal forebrain dynamics during a tactile discrimination task. J Neurophysiol. 2014 Sep 1;112(5):1179-91.

Omega-3 deficiency and neurodegeneration in the substantia nigra: involvement of increased nitric oxide production and reduced BDNF expression

Henriqueta Dias Cardoso, Eraldo Fonseca dos Santos Junior, David Filipe de Santana, Catarina Gonçalves-Pimentel, Monara Kaélle Angelim, Alinny R. Isaac, Cláudia Jacques Lagranha, Rubem Carlos Araújo Guedes, Eduardo Isidoro Beltrão, Edgar Morya, Marcelo Cairrão Araújo Rodrigues, Belmira Lara da Silveira Andrade-da-Costa. Omega-3 deficiency and neurodegeneration in the substantia nigra: involvement of increased nitric oxide production and reduced BDNF expression. Biochim Biophys Acta. 2014 Jun; 1840(6):1902-12.

Chronic, wireless recordings of large-scale brain activity in freely moving rhesus monkeys

David A Schwarz, Mikhail A Lebedev, Timothy L Hanson, Dragan F Dimitrov, Gary Lehew, Jim Meloy, Sankaranarayani Rajangam, Vivek Subramanian, Peter J Ifft, Zheng Li, Arjun Ramakrishnan,     Andrew Tate, Katie Z Zhuang, Miguel A L Nicolelis. Chronic, wireless recordings of large-scale brain activity in freely moving rhesus monkeys. Nat Methods. 2014 Jun;11(6):670-6.

Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links

Rico Rueedi, Mirko Ledda, Andrew W. Nicholls, Reza M. Salek, Pedro Marques-Vidal, Edgard Morya, Koichi Sameshima, Ivan Montoliu, Laeticia Da Silva, Sebastiano Collino, François-Pierre Martin, Serge Rezzi, Christoph Steinbeck, Dawn M. Waterworth, Gérard Waeber, Peter Vollenweider, Jacques S. Beckmann, Johannes Le Coutre, Vincent Mooser, Sven Bergmann, Ulrich K. Genick, Zoltán Kutalik. Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links. PLoS Genet. 2014 Feb 20; 10(2):e1004132.

Chronic Spinal Cord Electrical Stimulation Protects Against 6-hydroxydopamine Lesions

Amol P. Yadav, Romulo Fuentes, Hao Zhang, Thais Vinholo, Chi-Han Wang, Marco Aurelio M. Freire, Miguel A. L. Nicolelis. Chronic Spinal Cord Electrical Stimulation Protects Against 6-hydroxydopamine Lesions. Scientific Reports Jan/2014.

GWAS of human bitter taste perception identifies new loci and reveals additional complexity of bitter taste genetics

Mirko Ledda, Zoltán Kutalik, Maria C. Souza Destito, Milena M. Souza, Cintia A. Cirillo, Amabilene Zamboni, Nathalie Martin, Edgard Morya, Koichi Sameshima, Jacques S. Beckmann, Johannes le Coutre, Sven Bergmann and Ulrich K. Genick. GWAS of human bitter taste perception identifies new loci and reveals additional complexity of bitter taste genetics. Hum Mol Genet. 2014 Jan 1;23(1):259-67.

Simultaneous top-down modulation of the primary somatosensory cortex and thalamic nuclei during active tactile discrimination

Pais-Vieira M, Lebedev MA, Wiest MC, Nicolelis MA. Simultaneous top-down modulation of the primary somatosensory cortex and thalamic nuclei during active tactile discrimination. J Neurosci. 2013 Feb 27;33(9):4076-93. doi: 10.1523/JNEUROSCI.1659-12.2013.

A Brain-Machine Interface Enables Bimanual Arm Movements in Monkeys

Peter J. Ifft, Solaiman Shokur, Zheng Li, Mikhail A. Lebedev, Miguel A. L. Nicolelis. A Brain-Machine Interface Enables Bimanual Arm Movements in Monkeys. Science Translational Medicine, Nov/ 2013 Vol 5 Issue 210.

Expanding the primate body schema in sensorimotor cortex by virtual touches of an avatar

Aug/2013 Solaiman Shokur, Joseph E. O’Doherty, Jesse A. Winans, Hannes Bleuler, Mikhail A. Lebedev, Miguel A. L. Nicolelis. Expanding the primate body schema in sensorimotor cortex by virtual touches of an avatar. Proceedings of the National Academy of Sciences (PNAS).

Cortical-amygdalar circuit dysfunction in a genetic mouse model of serotonin deficiency

Dzirasa K, Kumar S, Sachs BD, Caron MG, Nicolelis MA. Cortical-amygdalar circuit dysfunction in a genetic mouse model of serotonin deficiency. J Neurosci. 2013 Mar 6;33(10):4505-13.

A Brain-to-Brain Interface for Real-Time. Sharing of Sensorimotor Information.

Feb/2013 Miguel Pais-Vieira, Mikhail Lebedev, Carolina Kunicki, Jing Wang, Miguel A. L. Nicolelis, A Brain-to-Brain Interface for Real-Time. Sharing of Sensorimotor Information. Scientific Reports 

Perceiving invisible light through a somatosensory cortical prosthesis

Eric E. Thomson, Rafael Carra, Miguel A.L. Nicolelis, Perceiving invisible light through a somatosensory cortical prosthesis. Nature Communications Feb/2013.

Mind in Motion

NICOLELIS, M. Mind in Motion. Scientific American, Sept./2012, p. 58 – 63

Appetitive changes during salt deprivation are paralleled by widespread neuronal adaptations in nucleus accumbens, lateral hypothalamus, and central amygdala

Tandon S, Simon SA, Nicolelis MA. Appetitive changes during salt deprivation are paralleled by widespread neuronal adaptations in nucleus accumbens, lateral hypothalamus, and central amygdala. J Neurophysiol. 2012 Aug;108(4):1089-105.

Reprogramming movements: extraction of motor intentions from cortical ensemble activity when movement goals change

Ifft PJ, Lebedev MA, Nicolelis MA. Reprogramming movements: extraction of motor intentions from cortical ensemble activity when movement goals change. Front Neuroeng. 2012 Jul 18;5:16.

Time-related effects of general functional training in spinal cord-injured rats

Miranda TA, Vicente JM, Marcon RM, Cristante AF, Morya E, Valle AC. Time-related effects of general functional training in spinal cord-injured rats. Clinics (Sao Paulo). 2012 Jul;67(7):799-804.

Subcortical neuronal ensembles: an analysis of motor task association, tremor, oscillations, and synchrony in human patients

Hanson TL, Fuller AM, Lebedev MA, Turner DA, Nicolelis MA. Subcortical neuronal ensembles: an analysis of motor task association, tremor, oscillations, and synchrony in human patients. J Neurosci. 2012 Jun 20;32(25):8620-32.

Spectral characteristics of the hippocampal LFP during contextual fear conditioning

Machado BS, Kunicki AC, Morya E, Sameshima K. Spectral characteristics of the hippocampal LFP during contextual fear conditioning. Einstein (Sao Paulo). 2012 Apr-Jun;10(2):140-4.

High-side digitally current controlled biphasic bipolar microstimulator

Hanson TL, Ómarsson B, O’Doherty JE, Peikon ID, Lebedev MA, Nicolelis MA. High-side digitally current controlled biphasic bipolar microstimulator. IEEE Trans Neural Syst Rehabil Eng. 2012 May;20(3):331-40.

The insular cortex controls food preferences independently of taste receptor signaling

Oliveira-Maia AJ, de Araujo IE, Monteiro C, Workman V, Galhardo V, Nicolelis MA. The insular cortex controls food preferences independently of taste receptor signaling. Front Syst Neurosci. 2012 Mar 1;6:5.

Glucose-dependent insulinotropic peptide receptor expression in the hippocampus and neocortex of mesial temporal lobe epilepsy patients and rats undergoing pilocarpine induced status epilepticus

Figueiredo CP, Antunes VL, Moreira EL, de Mello N, Medeiros R, Di Giunta G, Lobão-Soares B, Linhares M, Lin K, Mazzuco TL, Prediger RD, Walz R. Glucose-dependent insulinotropic peptide receptor expression in the hippocampus and neocortex of mesial temporal lobe epilepsy patients and rats undergoing pilocarpine induced status epilepticus. Peptides. 2011 Apr; 32(4):781-9. Epub 2010 Dec 23.

Adaptive decoding for brain-machine interfaces through Bayesian parameter updates

Li Z, O’Doherty JE, Lebedev MA, Nicolelis MA. Adaptive decoding for brain-machine interfaces through Bayesian parameter updates. Neural Comput. 2011 Dec; 23(12):3162-204.

Cortical correlates of fitts’ law

Ifft PJ, Lebedev MA, Nicolelis MA. Cortical correlates of fitts’ law. Front Integr Neurosci. 2011 Dec 22;5:85.

Future developments in brain-machine interface research

Lebedev MA, Tate AJ, Hanson TL, Li Z, O’Doherty JE, Winans JA, Ifft PJ, Zhuang KZ, Fitzsimmons NA, Schwarz DA, Fuller AM, An JH, Nicolelis MA. Future developments in brain-machine interface research. Clinics (Sao Paulo). 2011;66 Suppl 1:25-32.

A distinctive subpopulation of medial septal slow-firing neurons promote hippocampal activation and theta oscillations

Zhang H, Lin SC, Nicolelis MA. A distinctive subpopulation of medial septal slow-firing neurons promote hippocampal activation and theta oscillations. J Neurophysiol. 2011 Nov; 106(5):2749-63.

Active tactile exploration using a brain-machine-brain interface

O’Doherty JE, Lebedev MA, Ifft PJ, Zhuang KZ, Shokur S, Bleuler H, Nicolelis MA. Active tactile exploration using a brain-machine-brain interface. Nature. 2011 Oct 5; 479(7372):228-31.

Intravascular food reward

Oliveira-Maia AJ, Roberts CD, Walker QD, Luo B, Kuhn C, Simon SA, Nicolelis MA. Intravascular food reward. PLoS One. 2011; 6(9):e24992.

Neuronal assembly detection and cell membership specification by principal component analysis

Lopes-Dos-Santos V, Conde-Ocazionez S, Nicolelis MA, Ribeiro ST, Tort AB. Neuronal assembly detection and cell membership specification by principal component analysis. PLoS One. 2011; 6(6):e20996. Epub 2011 Jun 15.

Sensitivity of genome-wide-association signals to phenotyping strategy: the PROP-TAS2R38 taste association as a benchmark

Genick UK, Kutalik Z, Ledda M, Destito MC, Souza MM, Cirillo CA, Godinot N, Martin N, Morya E, Sameshima K, Bergmann S, le Coutre J. Sensitivity of genome-wide-association signals to phenotyping strategy: the PROP-TAS2R38 taste association as a benchmark. PLoS One. 2011; 6(11):e27745.

Impaired limbic gamma oscillatory synchrony during anxiety-related behavior in a genetic mouse model of bipolar mania

Dzirasa K, McGarity DL, Bhattacharya A, Kumar S, Takahashi JS, Dunson D, McClung CA, Nicolelis MA. Impaired limbic gamma oscillatory synchrony during anxiety-related behavior in a genetic mouse model of bipolar mania. J Neurosci. 2011 Apr 27; 31(17):6449-56.

Gustatory and reward brain circuits in the control of food intake

Oliveira-Maia AJ, Roberts CD, Simon SA, Nicolelis MA. Gustatory and reward brain circuits in the control of food intake. Adv Tech Stand Neurosurg. 2011; 36:31-59.

Chronic in vivo multi-circuit neurophysiological recordings in mice

Dzirasa K, Fuentes R, Kumar S, Potes JM, Nicolelis MA. Chronic in vivo multi-circuit neurophysiological recordings in mice.  J Neurosci Methods. 2011 Jan 30;195(1):36-46.

Different kinds of subjective experience during lucid dreaming may have different neural substrates

Mota-Rolim, SA, Erlacher, D, Tort, ABL, Araujo, JF, Ribeiro, S. Different kinds of subjective experience during lucid dreaming may have different neural substrates. International Journal of Dream Research, v. 3, p. 33-35, 2010.

Lithium ameliorates nucleus accumbens phase-signaling dysfunction in a genetic mouse model of mania

Dzirasa K, Coque L, Sidor MM, Kumar S, Dancy EA, Takahashi JS, McClung CA, Nicolelis MA. Lithium ameliorates nucleus accumbens phase-signaling dysfunction in a genetic mouse model of mania. J Neurosci. 2010 Dec 1; 30(48):16314-23.

What determines neurogenic competence in glia?

Costa, Marcos Romualdo; Götz, Magdalena; Berninger, Benedikt. What determines neurogenic competence in glia? Brain Research Reviews, v. 63, p. 47-59, 2010.

Does cell lineage in the developing cerebral cortex contribute to its columnar organization?

Costa, MR, Hedin-Pereira, C. Does cell lineage in the developing cerebral cortex contribute to its columnar organization? Frontiers in Neuroanatomy, vol. 4, Article 26, 2010. doi: 10.3389/fnana.2010.00026.

Spike avalanches exhibit universal dynamics across the sleep-wake cycle

Ribeiro TL1, Copelli M, Caixeta F, Belchior H, Chialvo DR, Nicolelis MA, Ribeiro S. Spike avalanches exhibit universal dynamics across the sleep-wake cycle. PLoS One. 2010 Nov 30;5(11):e14129.

Spinal cord stimulation failed to relieve akinesia or restore locomotion in Parkinson disease

Nicolelis MA, Fuentes R, Petersson P, Thevathasan W, Brown P. Spinal cord stimulation failed to relieve akinesia or restore locomotion in Parkinson disease. Neurology. 2010 Oct 19;75(16):1484; author reply 1484-5.

Spatiotemporal coupling between hippocampal acetylcholine release and theta oscillations in vivo

Zhang H, Lin SC, Nicolelis MA. Spatiotemporal coupling between hippocampal acetylcholine release and theta oscillations in vivo. J Neurosci. 2010 Oct 6; 30(40):13431-40.

Restoration of locomotive function in Parkinson’s disease by spinal cord stimulation: mechanistic approach

Fuentes R, Petersson P, Nicolelis MA. Restoration of locomotive function in Parkinson’s disease by spinal cord stimulation: mechanistic approach. Eur J Neurosci. 2010 Oct; 32(7):1100-8.

Activation of frontal neocortical areas by vocal production in marmosets

Simões CS, Vianney PV, de Moura MM, Freire MA, Mello LE, Sameshima K, Araújo JF, Nicolelis MA, Mello CV, Ribeiro S. Activation of frontal neocortical areas by vocal production in marmosets. Front Integr Neurosci. 2010 Sep 23; 4. pii: 123.

Oscillations trumped by behavior: a link between sensory and direct electrical stimulation of cortical activity

Tort AB, Katz DB. Oscillations Trumped by Behavior: A Link between Sensory and Direct Electrical Stimulation of Cortical Activity. Front Neurosci. 2010 Sep 15;4. pii: 39.

Measuring phase-amplitude coupling between neuronal oscillations of different frequencies

Tort AB, Komorowski R, Eichenbaum H, Kopell N. Measuring phase-amplitude coupling between neuronal oscillations of different frequencies. J. Neurophysiol. 2010 Aug; 104(2):1195-210. Epub 2010 May 12.

Changes in S1 neural responses during tactile discrimination learning

Wiest MC, Thomson E, Pantoja J, Nicolelis MA. Changes in S1 neural responses during tactile discrimination learning. J Neurophysiol. 2010 Jul; 104(1):300-12.

Expression of the immediate-early gene egr-1 and substance P in the spinal cord following locomotor training in adult rats

Nunes AC, Duarte RB, Sousa TB, dos Santos JR, Freire MA, Costa MS. Expression of the immediate-early gene egr-1 and substance P in the spinal cord following locomotor training in adult rats. Brain Res. 2010 Jul 23;1345:125-36. Epub 2010 Jun 11.

On building meaning: a biologically-inspired experiment on symbol-based communication

Loula A, Gudwin R, Ribeiro S, Queiroz. J. On building meaning: a biologically-inspired experiment on symbol-based communication. Adv Exp Med Biol. 2010; 657:77-93.

Noradrenergic control of cortico-striato-thalamic and mesolimbic cross-structural synchrony

Dzirasa K, Phillips HW, Sotnikova TD, Salahpour A, Kumar S, Gainetdinov RR, Caron MG, Nicolelis MA. Noradrenergic control of cortico-striato-thalamic and mesolimbic cross-structural synchrony. J Neurosci. 2010 May 5; 30(18):6387-97.

Cortical networks produce three distinct 7-12 Hz rhythms during single sensory responses in the awake rat

Tort AB, Fontanini A, Kramer MA, Jones-Lush LM, Kopell NJ, Katz DB. Cortical networks produce three distinct 7-12 Hz rhythms during single sensory responses in the awake rat. J Neurosci. 2010 Mar 24; 30(12):4315-24.

Minocycline treatment reduces white matter damage after excitotoxic striatal injury

Guimarães JS, Freire MA, Lima RR, Picanço-Diniz CW, Pereira A, Gomes-Leal W. Minocycline treatment reduces white matter damage after excitotoxic striatal injury. Brain Res. 2010 May 6;1329:182-93. Epub 2010 Mar 11.

Electrophysiological effects of guanosine and MK-801 in a quinolinic acid-induced seizure model

Torres FV, da Silva Filho M, Antunes C, Kalinine E, Antoniolli E, Portela LV, Souza DO, Tort AB. Electrophysiological effects of guanosine and MK-801 in a quinolinic acid-induced seizure model. Exp Neurol. 2010 Feb; 221(2):296-306. Epub 2009 Dec 4.

Licking-induced synchrony in the taste-reward circuit improves cue discrimination during learning

Gutierrez R, Simon SA, Nicolelis MA. Licking-induced synchrony in the taste-reward circuit improves cue discrimination during learning. J Neurosci. 2010 Jan 6; 30(1):287-303.

Theta-gamma coupling increases during the learning of item-context associations

Tort AB, Komorowski RW, Manns JR, Kopell NJ, Eichenbaum H. Theta-gamma coupling increases during the learning of item-context associations. Proc Natl Acad Sci USA. 2009 Nov 23.

Taste-guided decisions differentially engage neuronal ensembles across gustatory cortices

MacDonald CJ1, Meck WH, Simon SA, Nicolelis MA. Taste-guided decisions differentially engage neuronal ensembles across gustatory cortices. J Neurosci. 2009 Sep 9;29(36):11271-82.

Pain modulation by nitric oxide in the spinal cord

Freire MA, Guimarães JS, Leal WG, Pereira A. Pain modulation by nitric oxide in the spinal cord. Front Neurosci. 2009 Sep; 3(2):175-81.

A brain-machine interface instructed by direct intracortical microstimulation

O’Doherty JE, Lebedev MA, Hanson TL, Fitzsimmons NA, Nicolelis MA. A brain-machine interface instructed by direct intracortical microstimulation. Front Integr Neurosci. 2009 Sep 1;3:20.

Three-dimensional, automated, real-time video system for tracking limb motion in brain-machine interface studies

Peikon ID, Fitzsimmons NA, Lebedev MA, Nicolelis MA. Three-dimensional, automated, real-time video system for tracking limb motion in brain-machine interface studies. J Neurosci Methods. 2009 Jun 15; 180(2):224-33.

Principles of neural ensemble physiology underlying the operation of brain-machine interfaces

Nicolelis MA1, Lebedev MA. Principles of neural ensemble physiology underlying the operation of brain-machine interfaces. Nat Rev Neurosci. 2009 Jul;10(7):530-40.

Unscented Kalman filter for brain-machine interfaces

Li Z, O’Doherty JE, Hanson TL, Lebedev MA, Henriquez CS, Nicolelis MA. Unscented Kalman filter for brain-machine interfaces. PLoS One. 2009 Jul 15;4(7):e6243.

Hyperdopaminergia and NMDA receptor hypofunction kdisrupt neural phase signaling

Dzirasa K, Ramsey AJ, Takahashi DY, Stapleton J, Potes JM, Williams JK, Gainetdinov RR, Sameshima K, Caron MG, Nicolelis MA. Hyperdopaminergia and NMDA receptor hypofunction kdisrupt neural phase signaling. J Neurosci. 2009 Jun 24;29(25):8215-24.

Acquiring local field potential information from amperometric neurochemical recordings

Zhang H1, Lin SC, Nicolelis MA. Acquiring local field potential information from amperometric neurochemical recordings. J Neurosci Methods. 2009 May 15; 179(2):191-200.

Persistent hyperdopaminergia decreases the peak frequency of hippocampal theta oscillations during quiet waking and REM sleep

Dzirasa K, Santos LM, Ribeiro S, Stapleton J, Gainetdinov RR, Caron MG, Nicolelis MA. Persistent hyperdopaminergia decreases the peak frequency of hippocampal theta oscillations during quiet waking and REM sleep. PLoS One. 2009; 4(4):e5238.

Spinal cord stimulation restores locomotion in animal models of Parkinson’s disease

Fuentes R, Petersson P, Siesser WB, Caron MG, Nicolelis MA. Spinal cord stimulation restores locomotion in animal models of Parkinson’s disease. Science. 2009 Mar 20; 323(5921):1578-82.

Extracting kinematic parameters for monkey bipedal walking from cortical neuronal ensemble activity

Fitzsimmons NA1, Lebedev MA, Peikon ID, Nicolelis MA. Extracting kinematic parameters for monkey bipedal walking from cortical neuronal ensemble activity. Front Integr Neurosci. 2009 Mar 9;3:3.

Mechanisms of secondary degeneration in the central nervous system during acute neural disorders and white matter damage

GUIMARÃES, J.S.; FREIRE, M.A.M.; LIMA, R.R.; SOUZA-RODRIGUES, R.D.; COSTA, A.M.R.; PICANÇO-DINIZ, C.W.; GOMES-LEAL, W. Mechanisms of secondary degeneration in the central nervous system during acute neural disorders and white matter damage. Revista de Neurología, mar/2009; Vol. 48 (6), p. 304-310.

Nicotine activates TRPM5-dependent and independent taste pathways

Oliveira-Maia AJ, Stapleton-Kotloski JR, Lyall V, Phan TH, Mummalaneni S, Melone P, Desimone JA, Nicolelis MA, Simon SA. Nicotine activates TRPM5-dependent and independent taste pathways. Proc Natl Acad Sci U S A. 2009 Feb 3; 106(5):1596-601.

Distinct patterns of electrical stimulation of the basolateral amygdala influence pentylenetetrazole seizure outcome

Cota VR, Medeiros D de C, Vilela MR, Doretto MC, Moraes MF. Distinct patterns of electrical stimulation of the basolateral amygdala influence pentylenetetrazole seizure outcome. Epilepsy Behav. 2009 Jan; 14 Suppl 1:26-31.

Cellular prion protein modulates defensive attention and innate fear-induced behaviour evoked in transgenic mice submitted to an agonistic encounter with the tropical coral snake Oxyrhopus guibei

Lobão-Soares B, Walz R, Prediger RD, Freitas RL, Calvo F, Bianchin MM, Leite JP, Landemberger MC, Coimbra NC. Cellular prion protein modulates defensive attention and innate fear-induced behaviour evoked in transgenic mice submitted to an agonistic encounter with the tropical coral snake Oxyrhopus guibei. Behav Brain Res. 2008 Dec 12; 194(2):129-37. Epub 2008 Jun 11.

Multisensory Processing of Gustatory Stimuli

Simon SA, de Araujo IE, Stapleton JR, Nicolelis MAL. Multisensory Processing of Gustatory Stimuli. Chemosensory Perception 1: 95-102, 2008.

Neuronal ensemble bursting in the basal forebrain encodes salience irrespective of valence

Lin SC, Nicolelis MA. Neuronal ensemble bursting in the basal forebrain encodes salience irrespective of valence. Neuron. 2008 Jul 10;59(1):138-49.

Baseline hippocampal theta oscillation speeds correlate with rate of operant task acquisition

Santos LM, Dzirasa K, Kubo R, Silva MT, Ribeiro S, Sameshima K, Valle AC, Timo-Iaria C. Baseline hippocampal theta oscillation speeds correlate with rate of operant task acquisition. Behav Brain Res. 2008 Jun 26; 190(1):152-5.

Histochemical characterization, distribution and morphometric analysis of NADPH diaphorase neurons in the spinal cord of the agouti

FREIRE, M. A. M.; TOURINHO, S. C.; GUIMARÃES, J. S.; OLIVEIRA, J. L. F.; PICANÇO-DINIZ, C. W.; GOMES-LEAL, W.; PEREIRA, A. Histochemical characterization, distribution and morphometric analysis of NADPH diaphorase neurons in the spinal cord of the agouti. Frontiers in Neuroscience, Maio/ 2008, V. 2 (2), p. 1 – 9. (863kb)

Differential effects of methylmercury intoxication in the rat’s barrel field as evidenced by NADPH diaphorase histochemistry

FREIRE, M. A. M.; OLIVEIRA, R. B.; PICANÇO-DINIZ, C. W.; PEREIRA JR., A. Differential effects of methylmercury intoxication in the rat’s barrel field as evidenced by NADPH diaphorase histochemistry. Neurotoxicology. Elsevier, 2007, v. 28, p. 175-181. (546kb)

Processing of tactile information by the hippocampus

PEREIRA, A.; RIBEIRO, S.; WIEST, M.; MOORE, L. C.; PANTOJA, J.; LIN, S; NICOLELIS, M. A. L. Processing of tactile information by the hippocampus. PNAS, November 13, 2007, v. 104, nº 46, p. 18286 – 18291.

Novel experience induces persistent sleep-dependent placiticy in the cortex but not in hippocampus

RIBEIRO, S.; SHI, X.; ENGELHARD, M.; ZHOU, Y.; ZHANG, H.; GERVASONI, D.; LIN, S.; WADA, K.; LEMOS, N. A. M.; NICOLELIS, M. A. L. Novel experience induces persistent sleep-dependent placiticy in the cortex but not in hippocampus. Frontiers in Neuroscience, Nov./2007, V. 1 (1), p. 1 – 13.

Ensembles of gustatory cortical neurons anticipate and discriminate between tastants in a single lick

STAPLETON, J.; LAVINE, M. L.; NICOLELIS, M. A. L.; SIMON, S. A. Ensembles of gustatory cortical neurons anticipate and discriminate between tastants in a single lick. Frontiers in Neuroscience, Nov./ 2007, V. 1 (1), p. 161 – 174.

Neuronal Activity in the Primary Somatosensory Thalamocortical Loop Is Modulated by Reward Contingency during Tactile Discrimination

PANTOJA, J.; RIBEIRO, S.; WIEST, M.; SOARES, E.; GERVASONI, D.; LEMOS, N. A. M.; NICOLELIS, M. A. L. Neuronal Activity in the Primary Somatosensory Thalamocortical Loop Is Modulated by Reward Contingency during Tactile Discrimination. The Journal of Neuroscience, September 26, 2007, v.27, nº 39, p. 10608 – 10620.

La Recherche

NICOLELIS, M. La penseé aux commandes. La Recherche, Juillet-Août/2007, nº 410, p. 68 – 72.

Seeking the Neural Code

NICOLELIS, M.; RIBEIRO, S. Seeking the Neural Code. Scientific American. Dec./2006, p. 70 – 77.

Symbols are not uniquely human

RIBEIRO, S.; LOULA, A. C.; ARAUJO, I.; GUDWIN, R. R.; QUEIROZ, J. Symbols are not uniquely human. Biosystems, v.90, p. 263 – 272, 2006.

The Evolution of Neural Systems for Sleep and Dreaming

RIBEIRO, S.; NICOLELIS, M. A. L. The Evolution of Neural Systems for Sleep and Dreaming. In: Jon Kaas. (Org.). Evolution of Nervous Systems. 1 ed. New York: Elsevier, 2006, v. 3, p. 451-464.

O pai da neurociência moderna

FREIRE, M A M. Santiago Ramón Y Cajal – O pai da neurociência moderna. Neurociências, Maio – Junho, 2006, v. 3, nº 3, p. 146 -147. (819kb)